"Evaluating the Effects of Submucosal Injection of Platelet Rich Plasma on Accelerating Orthodontic Tooth Movement During Leveling and Alignment Stage

الملخص

To evaluate the effectiveness of injection of platelet rich plasma (PRP) in accelerating orthodontic tooth movement of crowded maxillary incisors.
This two-arm, parallel-group, randomized controlled trial involved 26 patients with severe to extreme maxillary incisors irregularity according to Little’s irregularity index,
indicating two first premolars extraction. Patients were randomly assigned to either the PRP group or the control group (13 each).
Following premolars extraction, orthodontic treatment with fixed
appliances was initiated for both groups. Immediately after insertion of the first archwire, patients in the PRP group receive the PRP injection , Alignment
progress was evaluated on the study casts taken before inserting the first archwire (T0), after 1
month of treatment commencement (T1), after 2 months (T2), and at the end of the leveling and
alignment stage (T3). Results: A statistically significant difference was found between the two groups in the overall treatment time (P > .001