المقارنة بين طريقتين من التخدير في العملية القيصرية عند الكلاب
الكلمات المفتاحية:
التخدير - العملية القيصرية – الكلاب
الملخص
أجري البحث على (12) كلبة حامل محلية بعمر (2-6) سنوات وبوزن (15-30) كغ، تم وضعها ضمن بوكسات خاصة للكلاب وضمن شروط صحية وتغذوية واحدة وذلك في كلية الطب البيطري بجامعة حماة.
بعد تشخيص الحمل باستخدام جهاز الإيكوغراف وقبل موعد الولادة بعدة أيام تم تقسيم الحيوانات عشوائياً إلى مجموعتين كل مجموعة ضمت ست كلبات: المجموعة الأولى: تم استخدام التخدير العام للعملية القيصرية: المركن زيلازين مع الكيتامين. المجموعة الثانية: تم استخدام التركين للعملية القيصرية: المركن زيلازين مع محلول المسكن الموضعي الليدوكائين 1%.
تم إجراء العملية القيصرية حسب الأصول لحيوانات التجربة، وتم تسجيل المؤشرات الاكلينيكية (معدل ضربات القلب – معدل حركات التنفس – معدل درجة الحرارة) بفواصل زمنية (قبل الحقن-بعد الحقن بـ 15د - بعد الحقن 30 د - بعد الحقن بـ 60د-بعد الحقن بـ 120د) وكذلك تم تسجيل بعض المعايير الدموية (عدد الكريات الحمراء–عدد الكريات البيضاء-عدد الصفيحات الدموية).
أظهرت النتائج تسجيل فروقات معنوية بسيطة في المؤشرات الاكلينيكية والدموية عند المقارنة بين المجموعتين وذلك بين الأنواع المختلفة من المركنات والمخدرات المستخدمة.
يستنتج من هذا البحث أن حقن الليدوكائين مع مركن الزيلازين كان الأفضل من الأمان والزمن حيث التأثيرات الجانبية.
المراجع
Alonso G.P.,Guedes C.,Tearny C.,Alessia C.,Fabio.,Jorg N.(2017): Comparison between the effects of postanaesthetic xylazine and dexmedetomidine on characteristics of recovery from sevoflurane anesthesia horses volume 44;Issue2,Pages 273-280.
Babalola Samuel Adeol Evaluatiom of the Subcutaneous Route for the Induction of Ketamine Anaesthesia in Dogs Global Veterinaria 13(3):293-296,2014a.
Bergström, A. (2009). Dystocia in the Bitch (Vol. 2009, No. 2009: 42).
Clarke, K. W., Trim, C. M., & Hall, L. W. (2014). General pharmacology of the injectable agents used in anaesthesia. Veterinary anaesthesia, 135, 55.
Concannon, P. W., & Hansel, W. (1977). Prostaglandin F2α induced luteolysis, hypothermia, and abortions in beagle bitches. Prostaglandins, 13(3), 533-542.
Darvelid, A. W., & Linde‐Forsberg, C. (1994). Dystocia in the bitch: A retrospective study of 182 cases. Journal of Small Animal Practice, 35(8), 402-407.
Enouri, S. S., Kerr, C. L., McDonell, W. N., & Dyson, D. H. (2008). Cardiopulmonary effects of anesthetic induction with thiopental, propofol, or a combination of ketamine hydrochloride and diazepam in dogs sedated with a combination of medetomidine and hydromorphone. American journal of veterinary research, 69(5), 586-595.
Gebremedhim Yohannes.,(2018):Hematological and Physiological Effect of Ketamine with and without Xylazine in Dogs Int J cell sci & mol boil 5(1):1-7.
Grasso s.c.;KO.J.C.;WELL A.B.,2015-Hemodynamic influence of acepromaaizene or dexmedetomidine premedication in isoflurane-anesthetized dogs.J AM Vet Assoc.246-764.
Hermanson, J. W., Evans, H. E., & de Lahunta, A. (2018). Miller and Evans' anatomy of the dog-E-book. Elsevier Health Sciences.
Hughes, W. L. (1981). The evolution of ophthalmic sutures. Annals of Plastic Surgery, 6(1), 48-65.
Ibrahim, A. (2017). Evaluation of total intra-venous anesthesia by ketamine-xyl-azine constant rate infusion in dogs: A novel preliminary dose study. Vet. Med. Open J, 2(2), 38-44.
Krishna,K.V.,Tiwari,R.D.and Raju,S.(2018):Effect on Haematological and Biochemical Profiles Following Administration of Ketamine Alone and in Combination with Dexmedetomidine or Butorphanol in Atropinized Dogint.J.Curr.Microbiol.App.Sci(2018)7(6):2568-2577.
Linde-Forsberg, C., & Eneroth, A. (2005). Abnormalities in pregnancy, parturition, and the periparturient period. Textbook of veterinary internal medicine, 7, 1890-1901.
Mathews, K. A. (2005). Analgesia for the pregnant, lactating and neonatal to pediatric cat and dog. Journal of veterinary emergency and critical care, 15(4), 273-284.
Mathews, K. A., & Dyson, D. H. (2005). Analgesia and chemical restraint for the emergent patient. Veterinary Clinics: Small Animal Practice, 35(2), 481-515.
Muir, W. W. (1985). Cyclohexanone drug mixtures: The pharmacology of ketamine and ketamine drug combinations. Proc. 2nd Intl. Cong. Vet. Anes, 5-14.
Mwangi E,Mogoa M,Nguhiu J,Mulei M(2014)Effects of epidural Ketamine,Xylazine and their combination on body temperature in acepromazine-sedated dogs.International Journal of Advanced Research 2:336-340.
Parrah J.D.,Hakim A.;Khadim H.;Bashir A.M.,2017-Evaluation of the Physiological and Anaesthetic Efficacy of Atropine-Xylazine-Diazepam –Ketamine Anesthesia in Non –Descriptive Dogs.J Anesth Pain Med.2(1),1-5.
Rahime the comparison of clinical and cardiopulmonary effects of xylazine,medetomidine and detomidine in dogs Ankara Univ Vet Fak Derg,65,313-322,2018.
Subhan, U.,Majid,A.,Sardar,H.,(2017):Effect of Xylazine and Ketamine on Pulse Rate,Respiratory Rate and Body Temperature in Dog J Avian,Volume 2 Issue 4 .p137-139.
Sugimoto, Y., Segi, E., Tsuboi, K., Ichikawa, A., & Narumiya, S. (1998). Female reproduction in mice lacking the prostaglandin F receptor. In Vasopressin and Oxytocin (pp. 317-321). Springer, Boston, MA.
Verstegen-Onclin, K., & Verstegen, J. (2008). Endocrinology of pregnancy in the dog: a review. Theriogenology, 70(3), 291-299.
Yohannes,G.(2018).Hematological and Physiological Effects of Ketamine with and without Xylazine in Dogs.Int J cell Sci and mol boil ,5(1):1-7.
Babalola Samuel Adeol Evaluatiom of the Subcutaneous Route for the Induction of Ketamine Anaesthesia in Dogs Global Veterinaria 13(3):293-296,2014a.
Bergström, A. (2009). Dystocia in the Bitch (Vol. 2009, No. 2009: 42).
Clarke, K. W., Trim, C. M., & Hall, L. W. (2014). General pharmacology of the injectable agents used in anaesthesia. Veterinary anaesthesia, 135, 55.
Concannon, P. W., & Hansel, W. (1977). Prostaglandin F2α induced luteolysis, hypothermia, and abortions in beagle bitches. Prostaglandins, 13(3), 533-542.
Darvelid, A. W., & Linde‐Forsberg, C. (1994). Dystocia in the bitch: A retrospective study of 182 cases. Journal of Small Animal Practice, 35(8), 402-407.
Enouri, S. S., Kerr, C. L., McDonell, W. N., & Dyson, D. H. (2008). Cardiopulmonary effects of anesthetic induction with thiopental, propofol, or a combination of ketamine hydrochloride and diazepam in dogs sedated with a combination of medetomidine and hydromorphone. American journal of veterinary research, 69(5), 586-595.
Gebremedhim Yohannes.,(2018):Hematological and Physiological Effect of Ketamine with and without Xylazine in Dogs Int J cell sci & mol boil 5(1):1-7.
Grasso s.c.;KO.J.C.;WELL A.B.,2015-Hemodynamic influence of acepromaaizene or dexmedetomidine premedication in isoflurane-anesthetized dogs.J AM Vet Assoc.246-764.
Hermanson, J. W., Evans, H. E., & de Lahunta, A. (2018). Miller and Evans' anatomy of the dog-E-book. Elsevier Health Sciences.
Hughes, W. L. (1981). The evolution of ophthalmic sutures. Annals of Plastic Surgery, 6(1), 48-65.
Ibrahim, A. (2017). Evaluation of total intra-venous anesthesia by ketamine-xyl-azine constant rate infusion in dogs: A novel preliminary dose study. Vet. Med. Open J, 2(2), 38-44.
Krishna,K.V.,Tiwari,R.D.and Raju,S.(2018):Effect on Haematological and Biochemical Profiles Following Administration of Ketamine Alone and in Combination with Dexmedetomidine or Butorphanol in Atropinized Dogint.J.Curr.Microbiol.App.Sci(2018)7(6):2568-2577.
Linde-Forsberg, C., & Eneroth, A. (2005). Abnormalities in pregnancy, parturition, and the periparturient period. Textbook of veterinary internal medicine, 7, 1890-1901.
Mathews, K. A. (2005). Analgesia for the pregnant, lactating and neonatal to pediatric cat and dog. Journal of veterinary emergency and critical care, 15(4), 273-284.
Mathews, K. A., & Dyson, D. H. (2005). Analgesia and chemical restraint for the emergent patient. Veterinary Clinics: Small Animal Practice, 35(2), 481-515.
Muir, W. W. (1985). Cyclohexanone drug mixtures: The pharmacology of ketamine and ketamine drug combinations. Proc. 2nd Intl. Cong. Vet. Anes, 5-14.
Mwangi E,Mogoa M,Nguhiu J,Mulei M(2014)Effects of epidural Ketamine,Xylazine and their combination on body temperature in acepromazine-sedated dogs.International Journal of Advanced Research 2:336-340.
Parrah J.D.,Hakim A.;Khadim H.;Bashir A.M.,2017-Evaluation of the Physiological and Anaesthetic Efficacy of Atropine-Xylazine-Diazepam –Ketamine Anesthesia in Non –Descriptive Dogs.J Anesth Pain Med.2(1),1-5.
Rahime the comparison of clinical and cardiopulmonary effects of xylazine,medetomidine and detomidine in dogs Ankara Univ Vet Fak Derg,65,313-322,2018.
Subhan, U.,Majid,A.,Sardar,H.,(2017):Effect of Xylazine and Ketamine on Pulse Rate,Respiratory Rate and Body Temperature in Dog J Avian,Volume 2 Issue 4 .p137-139.
Sugimoto, Y., Segi, E., Tsuboi, K., Ichikawa, A., & Narumiya, S. (1998). Female reproduction in mice lacking the prostaglandin F receptor. In Vasopressin and Oxytocin (pp. 317-321). Springer, Boston, MA.
Verstegen-Onclin, K., & Verstegen, J. (2008). Endocrinology of pregnancy in the dog: a review. Theriogenology, 70(3), 291-299.
Yohannes,G.(2018).Hematological and Physiological Effects of Ketamine with and without Xylazine in Dogs.Int J cell Sci and mol boil ,5(1):1-7.
منشور
2025-01-09
كيفية الاقتباس
حمويع. (2025). المقارنة بين طريقتين من التخدير في العملية القيصرية عند الكلاب. مجلة جامعة حماة, 7(14). استرجع في من https://hama-univ.edu.sy/ojs/index.php/huj/article/view/2202
القسم
قسم الطب البيطري
